AAV Design & Manufacturing Scientist

Full Time

GrittGene Therapeutics is looking for: Virus Production Scientist 

A qualified Virus Production Scientist will perform daily laboratory experimentation to successfully execute research-grade virus projects. This individual will be part of a manufacturing team handling high-throughput processing of viral vectors.

GrittGene Therapeutics general information about company mission & goals: 

1 in 4000 people worldwide could be affected by a Myotonic Dystrophy Type 2 which is a rare disease: that's more than 1.5 million people all over the world! As a new Exploratory AAV Gene Therapy scientist, a qualified candidate will have an opportunity to be part of a team to develop innovative medicines that can improve the lives and health of patients suffering from genetic diseases.

At GrittGene Therapeutics, our Mission is to cure patients with Myotonic Dystrophy Type 2. In our hands, alleviation of disease symptoms is just an observable effect of the cure. We develop the cure of tomorrow by combining all the tools available today. With our disease-centric approach, with the cure being the main driving force, GrittGene’s interdisciplinary platform is free from the constraints of big pharma. The collaborative environment at GrittGene combines the power of expert scientists from various branches of the pharmaceutical industry. We employ cutting-edge technologies including CRISPR and Artificial Intelligence to achieve unprecedented tissue-specific delivery of small-molecule treatment and gene-specific editing. We are not limited by internal technology; we are free to develop treatment the right way through collaboration and a combination of the complete pool of technologies and wealth of knowledge at our disposal today.

With the freedom to use a wide range of expertise and experiences through collaboration with the private sector, clinicians and academia we are armed with the technologies to be used to achieve a singular goal, CURE. Our goal is to provide a collaborative platform where the accumulated Knowledge, Experience, Relationships, Networks & Partnerships will come together to accomplish our mission.

Job Summary: The responsibilities include but are not limited to: 

  • Implement knowledge/expertise to successfully execute virus developmental projects for viral vectors (AAV, LVV, Adv, RVV, others)
  • Develop and confirm viral vector process including cell lines and downstream purification to ensure the optimized transition between teams
  • Work under the direction of senior scientists to promote internal research
  • Conduct independent process characterization and execute the operational procedures of viral vector productions to increase yield and quality
  • Work with Production to qualify and validate viral vector testing processes
  • Participate in decision-making processes within the project team by actively engaging in scientific and technical discussions
  • Build credibility within the lab group by performing high-quality work
  • Write, review, and revise production SOPs as aligned with updated procedures
  • Other duties as assigned


Minimum requirements (Job Qualifications):

  • B.S. in Biology, Biochemistry, Molecular Biology, or related field with 5+ years of experience, or
  • Master's degree in Biology, Biochemistry, Molecular Biology, or related field with 3+ years of experience
  • Working experience with virus production and/or cell culture is preferred
  • Excellent verbal and written communication skills
  • Microsoft Office experience (Word, Excel, PowerPoint, etc.)

EEO Statement:  
GrittGene Therapeutics is Equal Opportunity Employers and takes pride in maintaining a diverse environment. We do not discriminate in recruitment, hiring, training, promotion, or any other employment practices for reasons of race, color, religion, gender, national origin, age, sexual orientation, marital or veteran status, disability, or any other legally protected status 

Our Team, Values, and Culture: 

We are building a diverse, interdisciplinary team of dreamers and doers. Forget incrementalism and leave low-risk ideas at the door. We’re looking for fellow visionaries hungry for real impact in reimagining every facet of how we cure disease. Some of our values: first principles thinking, burning passion, and a drive to work with like-minded people; thinking outside the box and the ability to envision that which has not yet been built; listen, then talk; don’t forget to have fun; cooperation, trust, ethics, and transparency.   

An exciting opportunity to join early stage start up biotech company: 

As experts in human drug discovery, we have worked hard to position the company for success and to expand our team. You’re joining an incredibly ambitious team at an early enough time to help us define our culture, choices, and success. We will have the highest expectations of you, just as we do of ourselves. Join us in building new generation therapeutics outside of ordinary constrains! 

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